Have you read the studies linking aspartame to changes in gut biome? For instance this one: http://www.ncbi.nlm.nih.gov/m/pubmed/25313461/ http://www.ncbi.nlm.

Have you read the studies linking aspartame to changes in gut biome? For instance this one: http://www.ncbi.nlm.nih.gov/m/pubmed/25313461/ http://www.ncbi.nlm.nih.gov/m/pubmed/25313461/ You may be right about aspartame. I'm not an expert. Perhaps that study was also disproven. But my larger point is that it's really, really hard to prove a negative to an acceptable standard. Particularly across all categories we care about, not just cancer and heart disease. Have the biome effects been disproven too?