Study: "anti-depressant effects observed in mice treated with rosemary extract..." Press release: "rosemary extract discovered to be an effective anti-depressa

Study: "anti-depressant effects observed in mice treated with rosemary extract..." Press release: "rosemary extract discovered to be an effective anti-depressant." Media release: "how a simple cup of tea could permanently cure your depression." Social media (et al.): "feeling depressed? try this simple, secret tea Starbucks doesn't want you to know about that cures depression, boosts your IQ and prevents cancer!" Cynicism aside, in an attempt to add something useful, there does seem to be some correlation between recall rate (memory) and rosemary extract, at least in certain disease states, with a parabolic dose curve (low = beneficial, high = detrimental). There has been some chatter as to the specific MOA, however I think the presence of carnosic acid (a terpene present in rosemary) may be relevant--it seems to have PDE-inhibitory properties as well as a correlation with changes in cAMP/gAMP transduction. Any effect is probably minor, however it's nonetheless intriguing. And if you care about the anecdotal/unproven cognitive benefits (ie, quite possibly placebo), many users online have reported benefits with PDE 4/5 inhibition (luteolin, artichoke extract ideally) combined with Forskolin (which you should always be careful about and know the source of because improper/unregulated extracts could be quite toxic). http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139869/ http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139869/