3 ms·
I guess you can never definitively prove it. However, given what we know about how the stress system works, how long-term high cortisol affects the brain, etc.,
by cpncrunch 12y ago
I guess you can never definitively prove it. However, given what we know about how the stress system works, how long-term high cortisol affects the brain, etc., it's pretty well established that long-term stress has certain measurable effects on structure of the brain. Also, there have been studies showing similar changes in brain chemistry in animals
to that seen in depressed patients, when put into socially stressful situations.
I'm not entirely sure what your differentiation is between "trigger" and "genesis" in this case. Can you explain?
- eivarv 12y agoI'm sorry, I don't think I made myself very clear:P My point, summed up, is one regarding definition. Maybe it's just pedantry, but I find that your use of cause (what I also describe as genesis) sort of implies that it is a progenitor - that it is a starting point of sorts. And what I'm suggesting is that there are other factors at play (biopsychosocial model) long before the culmination of the disease in a major depressive episode - provided we are still talking about the term "depression" as in "major depressive disorder."
- cpncrunch 12y agoIn the cases I have witnessed, life events have been the progenitor. There are obviously other factors, such as personality, genetics, etc. However, life events seem to have been the main "cause" of these depressive episodes (and not just the trigger).