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There are tricky ways to get vm86 working with 64-bit operating systems, although it's not as nice as with 32-bit. Edit: An edit went on the wrong comment some

There are tricky ways to get vm86 working with 64-bit operating systems, although it's not as nice as with 32-bit. Edit: An edit went on the wrong comment somehow. Ignore what it said.

pdw 12y ago
And indeed, Wine can run 16-bit Windows applications on 64-bit Linux. You could say that at this point Linux is more Windows-compatible than Windows itself :)