It's currently an 'ayahuasca-boom' going on, that is taken advantage of by many locals who want to earn easy money. Another risk is that some of the shamans mix

It's currently an 'ayahuasca-boom' going on, that is taken advantage of by many locals who want to earn easy money. Another risk is that some of the shamans mix in other plants than the core ingredients, which can be dangerous. There is also the possibility of unwanted interactions with pharmaceuticals. With proper research and preparation, the 'jungle juice' is remarkably safe to consume.