Well, in fact the CH340 can be a problem, at least for Macs. The manufacturer's own driver is unsigned, so for years you had to disable kernel security feature

Well, in fact the CH340 can be a problem, at least for Macs. The manufacturer's own driver is unsigned, so for years you had to disable kernel security features just to run it, and with the latest OS X release, it causes kernel panics outright. There is an excellent third party driver at https://www.mac-usb-serial.com https://www.mac-usb-serial.com, but the $7 for that (in itself a very reasonable price) start pushing the clones back toward the price range of the originals.