4 ms·
Chronic fatigue syndrome is mitochondrial disease. The only reason there's any dispute over it is that OXPHOS testing is not standardized and so doctors are scr
by Madmallard 12y ago
Chronic fatigue syndrome is mitochondrial disease. The only reason there's any dispute over it is that OXPHOS testing is not standardized and so doctors are scrambling to put any meaning behind all these symptoms.
Chronic fatigue triggers -> medicines (many of them are starting to be known for being cytotoxic - bacteriocidal antibiotics anyone?),
surgery (plenty of well-known mito diseases are triggered by general anesthesia or exacerbated by), severe infections (energy saps of the body that can throw off the energy homeostasis greatly even in normal people).
Hell depression and anxiety may even be mitochondrial disease manifestations in the brain in some cases.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680051/ http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680051/
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3760005/ http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3760005/
http://www.ncbi.nlm.nih.gov/pubmed/22579150/ http://www.ncbi.nlm.nih.gov/pubmed/22579150/
http://www.mitoaction.org/files/Dykens%20for%20Mitoaction.pdf http://www.mitoaction.org/files/Dykens%20for%20Mitoaction.pd...
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2763246/ http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2763246/
http://triggered.stanford.clockss.org/ServeContent?rft_id=info:doi/10.1124/mi.5.2.7 http://triggered.stanford.clockss.org/ServeContent?rft_id=in...
It's completely fucking tragic that society has to demonize mental illness and all these debilitating diseases that we are causing ourselves in many cases. It's a fucking luck of the draw whether or not it will destroy you and possibly harm your future lineage.
It makes sense that stress reduction helps some people because stress uses up a lot of energy. That's less energy for maintaining homeostasis in a weak metabolic system.
One open question is to whether it is secondary or primary mitochondrial disease.