5 ms·
This is the most important question in this thread (though it was worded confusingly). There was a statistically discernible difference, but what is the magnitu
by magicalist 12y ago
This is the most important question in this thread (though it was worded confusingly). There was a statistically discernible difference, but what is the magnitude of that difference?
The reddit thread[0] on this paper has a lot of nonsense, but also has people with actual access to the paper. One informative comment (keeping in mind this study was done only on people who already identified as gluten sensitive):
> 31 of the individuals had an equal response to gluten or placebo, a further 13 had no significant difference. 5 individuals had stronger negative effects to placebo, 9 had stronger effects to Gluten. The three mentioned were over 2 standard deviations above the mean, and hence considered to be sensitive.
> There did appear to be a general increase across the board for symptoms, however the one caveat that was reported in results, but not discussed was the fact that individuals report worse symptoms (p=0.009) in the first week of the trial compared to the second.
> There were also no individual symptoms that showed a significant difference between the placebo and gluten. Only when all symptoms were combined as a sum did they have a difference.
[0] https://www.reddit.com/r/science/comments/2x844y/randomized_doubleblind_placebocontrolled_trial/coxt7iw https://www.reddit.com/r/science/comments/2x844y/randomized_...
- wbhart 12y agoI'm very surprised by those figures. Is that saying of 58 people studied, if 2 more people had stronger negative effects to placebo than Gluten then there'd be no discernible difference between placebo and Gluten? How does that show a significant correlation?
- windsurfer 12y agoSo only 9 of the 61 individuals that thought they had "gluten-sensitivity" actually reacted to the gluten, and only 3 were strongly affected by the gluten. I don't understand statistics very well... is that really significant enough?