I didn't see mention of the thing that always bothered me most: eye strain. I'm not sure if this is still an issue with newer "Retina"-style displays, but if

I didn't see mention of the thing that always bothered me most: eye strain. I'm not sure if this is still an issue with newer "Retina"-style displays, but if I recall correctly, the human eye will constantly try and refocus on individual pixels while reading online. This comes across to the reader initially as distractedness, and after prolonged periods, eye strain.