4 ms·
Two positive trials, but if there are additional negative trials those can be ignored. There is no requirement to combine all available trials in a meta-analysi
by kirsebaer 12y ago
Two positive trials, but if there are additional negative trials those can be ignored. There is no requirement to combine all available trials in a meta-analysis. Very easy for the pharm company to come up with some excuse to throw away "bad" data.
- refurb 12y agoI don't disagree, but I also don't think it's a bad thing. Most of the time the multiple failed trials occur in diseases where our current tools for measuring effect suck (CNS drugs). The FDA acknowledges this. Keep in mind that drug companies must submit all clinical trial data to the FDA (including all of the failures). It's not like the drug companies are pulling a fast one on the FDA. The FDA is looking at the totality of the evidence and making a call.