I was in a very similar situation 4 years ago when I switched from 100% .NET work in my local area to 100% Ruby/Rails work remotely. The first suggestion would

I was in a very similar situation 4 years ago when I switched from 100% .NET work in my local area to 100% Ruby/Rails work remotely. The first suggestion would be to join a Javascript developers meetup in your area. If there isn't one, start one on MeetUp.com. Network with other folks who are interested in these technologies and start collaborating with a few of them on some interesting side projects. You may even find an development manager that wants to hire experienced folks interested in learning Node, EmberJS, etc. Once you have something significant to shop around to more influential folks, it's just a matter of time before you'll land your first gig away from .NET land. The only caveat is you should plan to take a pay cut for your first non .NET gig, because it will likely be at a small company or startup and they will discount your experience. Once you have a bit more experience, you should be back to your old .NET salary in no time by switching to a larger shop within a year or two. Good luck!