You can use bootstrap with it, at least the HTML/CSS part. But for the JS part, you don't really need most of those tools most of the time. I worked with a few

You can use bootstrap with it, at least the HTML/CSS part. But for the JS part, you don't really need most of those tools most of the time. I worked with a few different companies doing SaaS, and we have always rolled a custom solution because of the designs. We never needed anything from bootstrap. To address your comment about knowledge not carrying over to the next framework down the line, what framework isn't like this? You always spend time learning the nuances of a framework that are never transferable.