... maybe put in setup.py something like from pip.req import parse_requirements requirements = parse_requirements("requirements.txt") setup( ... install_re

... maybe put in setup.py something like from pip.req import parse_requirements requirements = parse_requirements("requirements.txt") setup( ... install_requires=[str(r.req) for r in requirements] http://stackoverflow.com/a/16624700/348081 http://stackoverflow.com/a/16624700/348081