Considering how many bacteria are out there, and how frequently many of them multiply, even a one in a quadrillion chance of a mutation providing a resistance b

Considering how many bacteria are out there, and how frequently many of them multiply, even a one in a quadrillion chance of a mutation providing a resistance benefit is barely a speed-bump in evolutionary terms. Their "thirty year" claim is a best guess, but as this is entirely random, it could be three hundred, and it could be three. Remember there's about 10^14 bacterial cells in the average human body, ten times the number of human cells. Everyone's a big petri dish. If you killed all but one in a billion you'd still have a whole bunch left.