Is it OK to try to establish a correlation between calorie intake and lifespan without taking into account variety in calorie spending, or a "life style"? It s

Is it OK to try to establish a correlation between calorie intake and lifespan without taking into account variety in calorie spending, or a "life style"? It seems that excess of calories have a big negative effect for an "idle/aged" lifestyle, and almost no effect for "hyper-active/young" lifestyle. It seems also related to urban vs. rural populations.