5 ms·
We pin-pointed DNA double-strand breaks using sequencing, and found very high correlation with genes damaged by cancer. For e.g. the "ERG" gene which fuses with
by noipv4 12y ago
We pin-pointed DNA double-strand breaks using sequencing, and found very high correlation with genes damaged by cancer. For e.g. the "ERG" gene which fuses with TMPRSS2 in prostate cancer was one of the genes in our list. http://www.nature.com/nmeth/journal/v10/n4/carousel/nmeth.2408-F4.jpg http://www.nature.com/nmeth/journal/v10/n4/carousel/nmeth.24...
More research should reveal that it's more than just pure luck :)