In theory minimal on the positive side. The only thing you'd care about is the amino acid profile of the proteins, which they are claiming is better than meat:

In theory minimal on the positive side. The only thing you'd care about is the amino acid profile of the proteins, which they are claiming is better than meat: > “What’s exciting to me is that we now have a completely different set of proteins that we can tune,” says Geistlinger. “We’re looking at yeasts and algae, which both have amino acid profiles that are superior to beef. We made something that used yeast from the brewery across the street. It came out like bratwurst!”