Pharo is the closest thing to a de facto standard. It has a huge following, perhaps even the biggest of all Smalltalk users. It's the reference implementation f

Pharo is the closest thing to a de facto standard. It has a huge following, perhaps even the biggest of all Smalltalk users. It's the reference implementation for Seaside, the best of the Smalltalk web frameworks. It's the reference implementation for Amber, the best of the client-side web tools. I see little reason to consider anything else.