According to https://people.xiph.org/~xiphmont/demo/neil-young.html https://people.xiph.org/~xiphmont/demo/neil-young.html the answer is no. 16bits is more than

According to https://people.xiph.org/~xiphmont/demo/neil-young.html https://people.xiph.org/~xiphmont/demo/neil-young.html the answer is no. 16bits is more than enough to cover the entire range a human ear can pick up (assuming the source material was mixed and sampled correctly).