I'd choose rails and pick up a copy of Ryan Bigg's book - https://leanpub.com/multi-tenancy-rails https://leanpub.com/multi-tenancy-rails Django is also a fine

I'd choose rails and pick up a copy of Ryan Bigg's book - https://leanpub.com/multi-tenancy-rails https://leanpub.com/multi-tenancy-rails Django is also a fine choice but Django lacks learning resources. I mean seriously, why aren't you Django guys writing books and recording screencasts?