Not unless hash collisions are also a security issue (see http://bugs.python.org/issue13703 http://bugs.python.org/issue13703). But it's much slower than a trad

Not unless hash collisions are also a security issue (see http://bugs.python.org/issue13703 http://bugs.python.org/issue13703). But it's much slower than a traditional hashtable hashing function and not much slower than a sha family hash. Maybe that's the sweet spot for your project, but I think most non-security uses of MD5 are because it already exists in most languages and is pretty universal