4 ms·

Here's you've just shown that you have no idea what Aubrey and SENS are proposing. Maybe, like with Hofstadter's book, you've just "read the introduction" and t

Here's you've just shown that you have no idea what Aubrey and SENS are proposing. Maybe, like with Hofstadter's book, you've just "read the introduction" and then stopped? >We have no idea which genes contribute to aging, and how, and even how many. In all likelihood a simply astronomical number of genes would have to be altered to extend life. The whole point of SENS is that it DOESN'T try to fiddle with metabolism (our genes). All of the genetic diseases you mention are different from the diseases of aging, so they're a bad example. SENS is all about maintenance and periodical repair (like with an antique car, for example). Every, say, 10 years you go in and they remove accumulated damage (which can only be present in a limited number of long-lived molecules) BEFORE it causes pathologies. Most of this can probably be done with your own immune system (you train it to recognize some molecules), and some of it will have to be done other ways (gene therapy to make your body produce certain enzymes, etc).

araneae 17y ago
I know exactly what he's proposing. What I am saying is that it won't work, because aging has to do with developmentally fixed processes. Sure, you can replace blood cells, but do you really think we can replace all your cells, including your neurons? If you want to go in for a complete brain transplant, be my guest.
MikeCapone 17y ago
> I know exactly what he's proposing. What I am saying is that it won't work, because aging has to do with developmentally fixed processes. No you don't know "exactly" what he's proposing, and you don't understand what senescence is, as you've made clear many times here. I'm starting to feel this isn't very productive so we should probably stop this conversation. > Sure, you can replace blood cells, but do you really think we can replace all your cells, including your neurons? If you want to go in for a complete brain transplant, be my guest. Here you show again that you have no idea what SENS is proposing and you are making up strawmen. If you want to criticize something, please learn about it first.

araneae 17y ago

I know exactly what he's proposing. What I am saying is that it won't work, because aging has to do with developmentally fixed processes. Sure, you can replace blood cells, but do you really think we can replace all your cells, including your neurons? If you want to go in for a complete brain transplant, be my guest.

MikeCapone 17y ago

> I know exactly what he's proposing. What I am saying is that it won't work, because aging has to do with developmentally fixed processes. No you don't know "exactly" what he's proposing, and you don't understand what senescence is, as you've made clear many times here. I'm starting to feel this isn't very productive so we should probably stop this conversation. > Sure, you can replace blood cells, but do you really think we can replace all your cells, including your neurons? If you want to go in for a complete brain transplant, be my guest. Here you show again that you have no idea what SENS is proposing and you are making up strawmen. If you want to criticize something, please learn about it first.