"Requiring higher confidence is an expensive choice that must be weighed closely." Confidence of effectiveness is very easy to get - you just need to find an e

"Requiring higher confidence is an expensive choice that must be weighed closely." Confidence of effectiveness is very easy to get - you just need to find an effective drug. e.g. when antibiotics were first tried - they are massively effective compared to previous treatments - you get high confidence of effectiveness from just a small sample size. A reason it is hard for new drugs to get high confidence is because they are only marginally better than existing drugs.