With the exception of wine. Short answer: No. Longer answer: Probably not. Anything that P/Invokes native code (regardless if it's a system dll, or the apps o

With the exception of wine. Short answer: No. Longer answer: Probably not. Anything that P/Invokes native code (regardless if it's a system dll, or the apps own dlls) it will just not run. They will crash/throw exceptions when called. Since these apps won't expect themselves to be running on a non-windows operating system the exceptions won't be caught and crash. This will probably include many, many 3rd party controls.