3 ms·
No PhD here, but IAMA T1D. I noticed from the actual study that candidates for the trial must be within 3 months of diagnosis to even be considered; so it seem
by bigtunacan 12y ago
No PhD here, but IAMA T1D.
I noticed from the actual study that candidates for the trial must be within 3 months of diagnosis to even be considered; so it seems they are trying to screen and find only those people who have just recently developed diabetes and reverse it early in the process. In a sense this is sort of like catching a soon to be T2D in the pre-diabetic phase and telling them to eat less and run more. (There is no offense intended in that previous statement; with an obese pre-diabetic (type 2) it is possible to stop the disease before things are too late through exercise and diet, this is not the case in with a Type 1).
This makes me question if this is an effective treatment ONLY when caught early; or if it could be useful for long time diabetics like myself.
Also this treatment addresses beta cell replacement which is one side, but it doesn't address the autoimmune side which is actually causing the beta cell destruction in the first place. So would this be a lifetime pill that is taken to continuously build new beta cells? As I see it in the autoimmune T1D case as the beta cells remain under attack this would not be a "cure" per se, but rather an ongoing treatment that would result in an overall better outcome and quality of life for a diabetic (given it works at all).
- dnautics 12y agoyou pretty much nailed all of my concerns about this (especially the pernicious concern about maintenance drugs), but if it works, hey, that's better than nothing.
- bigtunacan 12y agoYeah; if I could take a pill a day like the T2D crowd with Metformin I would prefer that any day to insulin therapy.