Thanks for the clarification about the FDR. Obviously, its calculation very much depends on the base rate probabilities and the sensitivity of the method. The m

Thanks for the clarification about the FDR. Obviously, its calculation very much depends on the base rate probabilities and the sensitivity of the method. The method's ability to detect bias very much depends on the type of bias being applied. When only a file-drawer bias is being used the method is unlikely to detect the presence of bias (because the power values are dramatically overestimated). On the other hand, if optional stopping and a file drawer are used, the method has a good chance of detecting bias (because all the reported experiments stop just as soon as they satisfy the p<.05 criterion). Ioannidis used some of my simulation results to calculate likelihood ratios, which are somewhat related to the FDR. Details are at http://www.sciencedirect.com/science/article/pii/S0022249613000278 http://www.sciencedirect.com/science/article/pii/S0022249613...