The article gives a lot of neat background, but primarily deconstructs a straw man argument. He does a pretty good job of presenting the actual argument for mi

The article gives a lot of neat background, but primarily deconstructs a straw man argument. He does a pretty good job of presenting the actual argument for microbiome experimentation at the end: >our genomes have had little time to adapt to modern life, but our microbiomes have had plenty. >It may be that a Hadza microbiome would work equally well in an American gut, but incompatibilities are also possible. The conquistadors proved as much. As they colonized South America, they brought with them European strains of Helicobacter pylori, a stomach bacterium that infrequently causes ulcers and stomach cancer, and these European strains also displaced native American ones. This legacy persists in Colombia, where some communities face a 25-fold higher risk of stomach cancer, most likely due to mismatches between their ancestral genomes and their H. pylori strains.