Usability for everyone is important but basically every modern webapp is not usuable if you disable javascript. Its akin to disabling X11 and trying to use a de

Usability for everyone is important but basically every modern webapp is not usuable if you disable javascript. Its akin to disabling X11 and trying to use a desktop app, maybe a few fallback to a console program you can use but not many. As for your other comments its like everything else you have your target users and you need to weigh the costs/benefits of having your app work for everyone vs. not at all for some users. If you're building an online mockup editor screen readers have zero importance, on the other hand if you're building a blog, screen readers might be very important. I think meteor does one thing quite well and thats make it easy to build "realtime webapps" i.e. webapps that have lots of user interaction/clicks, etc. This is not something you would use to build news site with lots of long text documents.