Not quite -- there are plenty of other layouts designed for modern use, some of which were designed via genetic algorithm: <http://mkweb.bcgsc.ca/carpalx/?full_

Not quite -- there are plenty of other layouts designed for modern use, some of which were designed via genetic algorithm: <http://mkweb.bcgsc.ca/carpalx/?full_optimization> http://mkweb.bcgsc.ca/carpalx/?full_optimization>. Colemak is, however, one of the best I've seen which maintains most of the "standard" keyboard shortcuts.