I honestly don't think it would be possible. College Football is something that is so culturally engrained in America that even tinkering with it a little bit

I honestly don't think it would be possible. College Football is something that is so culturally engrained in America that even tinkering with it a little bit (like adding a tiny 4 team playoff) is met with huge amounts of skepticism. The MLB's system is also different because, on average, it takes longer to develop the typical player post-college. Obviously there are player outliers, but baseball is much more technical than football - which sort of justifies the entire farm system in and of itself. The incubation period is just typically longer.