Reading further about its mechanism of action[1], it seems like it decouples the electron transport chain. There are other substances (for example, the famous D

Reading further about its mechanism of action[1], it seems like it decouples the electron transport chain. There are other substances (for example, the famous DNP fat burner) that do this was well, and they all seems to have a narrow therapeutic index[2]. Take home message: Don´t mess with the mitochondria and, as you commented, research into its therapeutic potential. "The dosage makes it either a poison or a remedy" [3] [1] http://en.wikipedia.org/wiki/Arsenic_toxicity#Mechanism http://en.wikipedia.org/wiki/Arsenic_toxicity#Mechanism [2] http://en.wikipedia.org/wiki/Therapeutic_index http://en.wikipedia.org/wiki/Therapeutic_index [3] http://www.brainyquote.com/quotes/quotes/p/paracelsus300347.html http://www.brainyquote.com/quotes/quotes/p/paracelsus300347....