4 ms·
It might be worth noting that there are other similar drugs already in widespread use for the same purpose. https://en.wikipedia.org/wiki/Naltrexone https://en
by rmxt 12y ago
It might be worth noting that there are other similar drugs already in widespread use for the same purpose.
https://en.wikipedia.org/wiki/Naltrexone https://en.wikipedia.org/wiki/Naltrexone
The submitted article doesn't seem to touch on what differentiates nalmefene from naltrexone, but the dubiously cited Wikipedia article for nalmefene mentions that advantages "include longer half-life, greater oral bioavailability and no observed dose-dependent liver toxicity." Both are recommended for use in conjunction with psychosocial support techniques.
- jrapdx3 12y agoThe article was disappointingly short of a few bits of information. It didn't describe the class of drug (opioid receptor blocker), give examples of similar drugs or even give a pointer to more complete information. Yeah, I know, I could look it up (and I will), but even in a brief announcement, I don't think a little more information is too much to ask for. Naltrexone has shown benefit for alcohol dependence, and other addictive behaviors too. Probably too obvious to say, but no drug is a "magic bullet" and risk of side-effects remains an important consideration. For naltrexone, a particular concern is liver toxicity with higher doses. The newer drug may be different, but a drug's bad effects may show up only after prolonged use. Registration trials may not be go on long enough, or involve enough subjects to reveal long-term or rare problems.
- ippster 12y agoWhile on Naltrexone I felt a create decline in cravings, although for Marijuana and not alcohol. The noticeable side effects to me was irritated stomach and feeling very tired and fatigued, which was a plus, sleeping on cannabis withdrawal is a major bitch.