The computing model, no, not really anything fundamentally different. It comes to tooling and profiling under Linux. Also, NVidia has slightly beefer cores and

The computing model, no, not really anything fundamentally different. It comes to tooling and profiling under Linux. Also, NVidia has slightly beefer cores and fewer ones, where as AMD has more cores (as I heard). Thus, for me, CUDA is a more complete tool-chain with proper compiler (nvcc), profiler (nvprof, nvvp) and libraries (cublas, cudnn, cufft).