If you know Python, it's an amazing language. Ruby and Javascript are incredibly useful for web dev, but like angersock said, the key is to build projects. Pe

If you know Python, it's an amazing language. Ruby and Javascript are incredibly useful for web dev, but like angersock said, the key is to build projects. Period. If Python's the language you feel most comfortable in, get going with it and don't switch until after a project is complete. I'd suggest Flask as a starting point if you're looking for web framework experience. Twisted might be more your style if you're looking at highly concurrent networking projects. 'Distributed systems' is a little broad almost- are there any software projects in particular in that space that you're interested in and could develop expertise in? If so, I'd focus there.