I'm glad to see advances being made. Schizophrenia is extremely hard to research. And it's devastating to the patient. In the early nineties I worked at the Un

I'm glad to see advances being made. Schizophrenia is extremely hard to research. And it's devastating to the patient. In the early nineties I worked at the University of Pennsylvania measuring brain MRIs as part of a schizophrenia study. They knew there was a strong genetic component, but they also knew that not everybody with a strong genetic weighting would develop the disorder. They had plenty of records of identical twins where one suffered from schizophrenia and the other did not. The model then was the Diathesis-Stress model [1]. The diathesis, or predisposition, is in the genes. They thought the stress could be one of a number of things: maternal infection while the baby was still developing, birth complications such as brief interruptions in oxygen flow, infections after the baby is born, and perhaps extreme psychological trauma, like combat. [1] http://en.wikipedia.org/wiki/Diathesis-stress_model http://en.wikipedia.org/wiki/Diathesis-stress_model