First of all: Rails is a framework Django is a framework Node.JS is a platform/framework ASP.NET is not a framework, but a language PHP is not a framework

First of all: Rails is a framework Django is a framework Node.JS is a platform/framework ASP.NET is not a framework, but a language PHP is not a framework but a language, HHVM is a platform That being said: you did not specify what exactly you are planing to do. For most scenarios, the choice of the environment doesn't really matter. What DOES matter is that you find someone that is proficient, has experience and knows the pros/cons in whatever framework he is using. If you really need minimal memory and CPU footprint, i'd suggest you choose Go.