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Its a very common phenomenon in science that a finding is published in a glamour journal e.g. Nature/Science and then if not immediately controversial e.g. acid

Its a very common phenomenon in science that a finding is published in a glamour journal e.g. Nature/Science and then if not immediately controversial e.g. acid bath stem cells, it becomes very difficult to publish something contradictory. Journal referees will set the bar for such findings very very high...and you are quite likely to be refereed by the original author or their friends. I know this to my cost having gone to extraordinary lengths to publish something slightly contradictory in a far lower impact journal than the work deserved.

learnstats2 12y ago
In general, if your results contradict existing science, your work for publication will be passed immediately to those scientists for "peer review". Those same scientists are motivated to protect their own existing and future work. The academic standards you are subjected to will be far higher than work supporting the status quo.
- rgejman 12y ago
  Unfortunately, they are usually also the best equipped to find flaws in the new work. True, this is not ideal, but it's also not ideal to send a paper to less expert reviewers. All of which goes to say that pre-print publication is the way to gooooo.