> Are there other paths of study relating to depression that have are gathering interesting evidence? Yes. One of the most promising is Deep Brain Stimulation:

> Are there other paths of study relating to depression that have are gathering interesting evidence? Yes. One of the most promising is Deep Brain Stimulation: http://www.nytimes.com/2006/04/02/magazine/02depression.html?pagewanted=all http://www.nytimes.com/2006/04/02/magazine/02depression.html... Quote: "As it turned out, 8 of the 12 patients he operated on, including Deanna, felt their depressions lift while suffering minimal side effects — an incredible rate of effectiveness in patients so immovably depressed. Nor did they just vaguely recover. Their scores on the Hamilton depression scale, a standard used to measure the severity of depression, fell from the soul-deadening high 20's to the single digits — essentially normal. They've re-engaged their families, resumed jobs and friendships, started businesses, taken up hobbies old and new, replanted dying gardens. They've regained the resilience that distinguishes the healthy from the depressed." I hasten to add that DBS is nowhere near ready for the clinic -- it's experimental and risky. But it shows what can happen when people are willing to consider biological explanations instead of psychological ones.