Gwern did a convincingly rigorous self-experiment with LSD microdosing. [1] He sums it up as, "No beneficial effects reached statistical-significance and there

Gwern did a convincingly rigorous self-experiment with LSD microdosing. [1] He sums it up as, "No beneficial effects reached statistical-significance and there were worrisome negative trends. LSD microdosing did not help me." [1] http://www.gwern.net/LSD%20microdosing http://www.gwern.net/LSD%20microdosing