Withdrawal from alcohol can literally kill you[0]. Withdrawal from opiates can also cause similar withdrawal symptoms, but is not fatal[1]. There are many ways

Withdrawal from alcohol can literally kill you[0]. Withdrawal from opiates can also cause similar withdrawal symptoms, but is not fatal[1]. There are many ways to judge the statement 'most harmful drug', so there's no bright line, but that's a pretty big mark against alcohol. [0] https://en.wikipedia.org/wiki/Delerium_tremens https://en.wikipedia.org/wiki/Delerium_tremens [1] Ibid.