Another thing about genetics is that it could probably affect appetite. You know how you feel if you haven't eaten for a day, no amount of will power is going

Another thing about genetics is that it could probably affect appetite. You know how you feel if you haven't eaten for a day, no amount of will power is going to stop you from eating. Now what if your genetics made you feel like that all the time? So sure you could lose weight if you ate less, but your genetics wouldn't make the motivation equation work out.