It's not based on Node.js, but CIRC is worth mentioning because it's pure JS IRC client that doesn't need a relay server: http://flackr.github.io/circ/ http://

It's not based on Node.js, but CIRC is worth mentioning because it's pure JS IRC client that doesn't need a relay server: http://flackr.github.io/circ/ http://flackr.github.io/circ/ https://github.com/flackr/circ https://github.com/flackr/circ It uses the chrome.socket APIs to connect directly to the IRC network.