Yes, but unlike a gamma-ray burst, there is literally no hope of survival. With a gamma-ray burst one could, in theory, survive given an ultra-shielded structur

Yes, but unlike a gamma-ray burst, there is literally no hope of survival. With a gamma-ray burst one could, in theory, survive given an ultra-shielded structure with full life support (to offset the lack of atmosphere and any other life on the surface once the burst passed). If a region of lower vacuum energy were headed our way, it would completely change the very physics we know of down to the sub-subatomic level. Ain't nothin' standing in the way of that...