pure JavaScript has too many ways to introduce subtle bugs into large projects, which also become a nightmare to maintain. From a hacker perspective, node.js an

pure JavaScript has too many ways to introduce subtle bugs into large projects, which also become a nightmare to maintain. From a hacker perspective, node.js and js are great. js is a beautiful and extremely powerful lang. From a "business" perspective -even more if your business data better fits a RDB-, IMHO, javascript, node.js+ a LARGE business project are a recipe for disaster. (If you add ORM to the mix, you're doomed). http://blog.codinghorror.com/object-relational-mapping-is-the-vietnam-of-computer-science/ http://blog.codinghorror.com/object-relational-mapping-is-th... I believe a compiler-to-js like Typescript makes using JavaScript+node in a large business project more manageable (disclaimer: I've not tried Typescript, but I've coded my own compile-to-js lang out to frustration with medium-to-large js projects: https://github.com/luciotato/LiteScript https://github.com/luciotato/LiteScript ) TL;DR: My two cents: Not a good business case for a business IF a classic RDB fits your business data.