Regardless of the meaning of the underlying domain, I believe it to be important to watch for easy typos or possibly lost meaning. Personally, but that may be

Regardless of the meaning of the underlying domain, I believe it to be important to watch for easy typos or possibly lost meaning. Personally, but that may be just me, I feel as though "openmined.com" is easily confused or typoed with "openminded.com". That alone is a risk of lost traffic.