Of the corner opening patterns alone (called joseki), there are 10000s of them, and it's very common to use novel ones. Many joseki, like the well known 4-4/3-3

Of the corner opening patterns alone (called joseki), there are 10000s of them, and it's very common to use novel ones. Many joseki, like the well known 4-4/3-3 invasion, can range from great plays to disasters depending on board position. And there are four corners.