(The parent comment references the "Life finds a way" quote from Jurassic Park, possibly in jest) Can't happen: Evolution is limited to small steps caused by m

(The parent comment references the "Life finds a way" quote from Jurassic Park, possibly in jest) Can't happen: Evolution is limited to small steps caused by mutation. First, there is nothing in a cell which creates anything remotely like the missing base-pairs so there is nothing available to mutate into a base-pair synthesizer. Second, as the cells are grown in a vat of artificial base-pairs, there is no evolutionary advantage to developing the ability to create base-pairs. It's like scurvy: humans have no evolutionary pressure (outside of 19th Century sailors) to suddenly start producing Vitamin C themselves because they eat fresh food.