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Yes; there are perverse disincentives built into the profit mechanism underpinning the commercial pharmaceutical industry. Patents on antibiotics last no longe
by cstross 13y ago
Yes; there are perverse disincentives built into the profit mechanism underpinning the commercial pharmaceutical industry.
Patents on antibiotics last no longer than on any other type of medicine (20 years, minus the substantial time taken to test it, jump through regulatory hoops, and bring it to market -- typically 8-14 years). The cost of meeting those regulatory prerequisites is measured in the hundreds of millions of dollars in the USA alone -- more if you want to get a product license everywhere worldwide. So you need to earn back several hundred million bucks in profit in a single-digit period of years ...
But antibiotics are unprofitable. A typical AB course lasts 5-14 days after which the patient is completely cured. Compare with antidepressants or ADHD drugs -- where you get a customer for life! Which would you invest in, if you were in that business -- a product 10% of the population will use annually for a week, or a product 10% of the population will be hooked on for life?
It's not a coincidence that research into new antibiotics ground to a halt in the 1970s around the time that the regulatory barriers to entry rose so high that small and medium scale pharmaceutical companies were frozen out of the business and the surviving operators were the large conglomerates.
(Disclaimer: wearing my ex-pharmacist hat here.)
- dopkew 13y agoI saw a documentary in which it was said that another disincentive to antibiotic research is that its very use causes its effectiveness (for the general population) to reduce, due to antibiotic resistance. So that it would eventually stop selling. It is not so in the case of medicines for BP, diabetes etc. We may eventually need to have a compulsory hospital stay (or something else) for antibiotic treatment so that a patient treated with an antibiotic does not have any leftover resistant pathogens to transfer to the public.