That's a pretty good prediction. Were I a betting man, my money would be on an explosion of females who can use some form of detection to suss out the defective

That's a pretty good prediction. Were I a betting man, my money would be on an explosion of females who can use some form of detection to suss out the defective gene based on some secondary characteristic. If those females can then evade mating with the altered males, their offspring would rapidly expand through the ecosystem (given that their niche would be cleared of in-species competitors). Jury's out on whether this change could happen before the mosquito population falls below sustainable levels, though. Mosquitos breed rapidly, but they don't hold a candle to bacteria breeding rates and it takes a lot of generations for those to evolve resistance to each generation of antibacterials.