From personal experience, I would absolutely say that a huge component of "desire" can be eliminated by a low glycemic diet (this is orthogonal to depression, I

From personal experience, I would absolutely say that a huge component of "desire" can be eliminated by a low glycemic diet (this is orthogonal to depression, I cannot speak to that). The blood sugar/insulin "roller coaster" can be avoided: rises in blood sugar stimulate an insulin response, insulin is released to move the glucose, but eventually this causes a dip which triggers (somewhat misleading) hunger pangs. The trick is to get this to happen as little/gently as possible and those pangs go away. I do it every day and I've lost weight for the past ~20 weeks without being hungry. No willpower is required, just consistency (and taking a great interest in it all...).